Invitrogen™ KIR3DS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA597295

Product Code. 16510132

Description

Immunogen sequence: FNMSPVTTAH AGNYTCRGSH PHSPTGWSAP SNPMVIMVTG NHRKPSLLAH PGPLVKSGER VILQCWSDIM FEHFFLHKEW ISKDPSRLVG QIHDGVSKAN FSIGSMMRAL AGTYRCYGSV THTPYQLSAP SDPLDIVVTG LYEKPSLSAQ PGPKVQAGES VTLSCSSRSS YDMYHLSREG GAHERRLPAV RKVNRTFQAD FPLGPATHGG TYRCFGSFRH SPYEWSDPSD PLLVSVTGNP SSSWPSPTEP SSKSGNLRHL H; Positive Samples: Jurkat, A-549, THP-1, BT-474, B-cell, Mouse liver, Mouse kidney, Mouse pancreas, Rat liver; Cellular Location: Cell membrane, Single-pass type I membrane protein.

The killer immunoglobulin-like receptors (KIRs) on natural killer (NK) cells regulate the inhibition and activation of NK-cell responses through recognition of human leukocyte antigen (HLA) class I molecules. KIR3DL1, a receptor for HLA-B antigens with the Bw4 allele, transmits an inhibitory signal to prevent killer cell-mediated cytoxicity. KIR3DL1 encodes a 444 amino acid type I transmembrane protein, containing three immunoglobulin-like C2-type domains.

Specifications

• Antigen: KIR3DS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KIR3DS1
• Gene Alias: CD158E2; killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1; killer cell immunoglobulin-like receptor 3DS1; killer cell immunoglobulin-like receptor KIR3DS1; killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1; killer Ig receptor; KIR-123FM; KIR3DS1; KIR-G1; MHC class I NK cell receptor; natural killer cell receptor; natural killer-associated transcript 10; NKAT10; NKAT-10
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3813
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.97 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q14943
• Gene Symbols: KIR3DS1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human KIR3DS1 (NP_0010770081).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG