Kir3.2 (KCNJ6) Polyclonal Antibody, Invitrogen™

Guinea Pig Polyclonal Antibody

Brand:  Invitrogen PA5111799

Product Code. 17149713

Description

Reconstitute antibody with 50 μL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min). GST fusion protein sequence is: ELANRAEVPL SWSVS SKLN QHAELETEEE EKNPEELTER NG Homology: Rat - 40/41, human - 37/41 amino acid residues identical.

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.

Specifications

• Antigen: Kir3.2 (KCNJ6)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNJ6
• Gene Alias: BIR1; G protein-activated inward rectifier potassium channel 2; GIRK2; GIRK-2; hiGIRK2; Inward rectifier K(+) channel Kir3.2; KATP2; KATP-2; KCNJ6; Kcnj7; KIR3.2; KPLBS; MGC126596; Potassium channel, inwardly rectifying subfamily J member 6; W; weaver; wv
• Host Species: Guinea Pig
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16522, 25743
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen), Western Blot
• Concentration: 0.8 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P48542, P48550
• Gene Symbols: KCNJ6
• Immunogen: GST fusion protein corresponding to residues 374-414 of mouse Kir3.2 (GIRK2)
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG