KIR2DL3/CD158b2 Antibody (GL183), Novus Biologicals™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
18234961	Novus Biologicals NB100-65875-0.025MG	0.025 mg
18075705	Novus Biologicals NB100-65875-0.1MG	0.1 mg

Description

KIR2DL3/CD158b2 Monoclonal specifically detects KIR2DL3/CD158b2 in Human samples. It is validated for Flow Cytometry, Immunoprecipitation.

Specifications

• Antigen: KIR2DL3/CD158b2
• Concentration: 1 mg/mL
• Applications: Flow Cytometry, Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Apoptosis
• Formulation: PBS, 0.5% Bovine Serum Albumin with 0.09% Sodium Azide
• Gene Alias: CD158 antigen-like family member B2, CD158b2 antigen, CD158B2CD158b, cl-6, killer cell immunoglobulin-like receptor 2DL3, killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3, Killer inhibitory receptor cl 2-3, KIR-023GB, KIRCL23, KIR-K7b, KIR-K7c, MGC129943, MHC class I NK cell receptor, natural killer associated transcript 2, natural killer cell inhibitory receptor KIR2DL3, Natural killer-associated transcript 2, NKAT, nkat2, NKAT-2, NKAT2a, NKAT2B, NKAT2GL183, NK-receptor, p58, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I specific NK receptor, p58.2 MHC class-I-specific NK receptor
• Gene Symbols: KIR2DL3
• Isotype: IgG1
• Purification Method: Protein A or G purified
• Test Specificity: NB100-65875 recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail. Both molecules are members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.

• Clone: GL183
• Dilution: Flow Cytometry 1:10-1:50, Immunoprecipitation 1:10-1:500
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human
• Gene Accession No.: P43628
• Gene ID (Entrez): 3804
• Immunogen: NK cell clone E57
• Primary or Secondary: Primary
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

For Research Use Only