Kir2.2 (KCNJ12) Mouse anti-Human, Mouse, Rat, Clone: S124B-38, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA527678

Product Code. 16302194

Description

Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Specifications

• Antigen: Kir2.2 (KCNJ12)
• Classification: Monoclonal
• Concentration: 1 mg/ml
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P52187, P52188, Q14500
• Gene Symbols: KCNJ12
• Immunogen: Fusion protein amino acids 362-427 of rat Kir2.2
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: S124B-38
• Conjugate: Unconjugated
• Gene: KCNJ12
• Gene Alias: IRK2, KCNJ12, kcnj12x, KCNJN1, Kir2.2v, potassium inwardly rectifying channel subfamily J member 12
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 117052, 16515, 3768
• Content And Storage: -20°C
• Form: Liquid