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  6. Kir2.1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Kir2.1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16869444 Shop All Proteintech Products
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150 μL
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150µL
20µL
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16869444 150 μL 150µL
16879444 20 μL 20µL
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Product Code. 16869444 Supplier Proteintech Supplier No. 199651AP150UL

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Description

Rabbit Polyclonal Antibody

The antibody recognizes the C-term of KCNJ2.

The KIR2 subunit family includes 2.1, 2.2, 2.3 and 2.4. Unlike G protein-coupled KIR3 subunits, KIR2.1 requires both phosphorylation by PKA and ATP hydrolysis for functional activity. KIR2.1 is expressed in the superior and inferior collicula and the pontine region of the brain, where it moderates synaptic transmission, like many other potassium channels. In the placenta, KIR2.1 is expressed throughout gestation in cytotrophoblast cells. In the kidney, KIR2.1 colocalizes with KIR5.1 in the proximal tubule. KIR2.1, 2.2 and 2.3 associate with the membrane-associated guanylate kinase synapseassociated protein 97 in the cerebellum and heart. Phosphorylation of KIR2.2 by protein kinase A inhibits the associates with SAP97.

Specifications

Antigen Kir2.1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene KCNJ2
Gene Accession No. P35561, P63252, Q64273
Gene Alias HHBIRK1, HHIRK1, hIRK1, IRK 1, IRK1, KCNJ2, Kir2.1, LQT7, SQT3
Gene Symbols Kcnj2
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16518, 29712, 3759
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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