Invitrogen™ Kir1.1 (KCNJ1) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA582946

Product Code. 16359904

Description

Immunogen sequence: STSATCQVRT SYVPEEVLWG YRFAPIVSKT KEGKYRVDFH NFSKTVEVET PHCAMCLYNE KDVRARMKRG YDNPNFILSE VNETD Highest antigen sequence indentity to the following orthologs: Rat - 94%, Mouse - 93%.

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Kir1.1 (KCNJ1)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNJ1
• Gene Alias: ATP-regulated potassium channel ROM-K; ATP-sensitive inward rectifier potassium channel 1; inward rectifier K(+) channel Kir1.1; inwardly rectifying K+ channel; inwardly rectifying potassium channel ROMK-2; K+ channel protein; KAB-1; Kcnj; Kcnj1; KIR1.1; LOW QUALITY PROTEIN: ATP-sensitive inward rectifier potassium channel 1; OTTHUMP00000045938; potassium channel, inwardly rectifying subfamily J member 1; potassium channel, inwardly rectifying subfamily J, member 1; potassium inwardly rectifying channel subfamily J member 1; potassium inwardly-rectifying channel J1; Potassium inwardly-rectifying channel subfamily J; potassium inwardly-rectifying channel, subfamily J, member 1; potassium voltage-gated channel subfamily J member 1; ROMK; ROMK1; Romk2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3758
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P48048
• Gene Symbols: KCNJ1
• Immunogen: Recombinant protein corresponding to Human KCNJ1. Recombinant protein control fragment (Product #RP-90994).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG