Invitrogen™ KIP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5104486

Product Code. 16670935

Description

Antibody detects endogenous levels of total CIB2.

DNA-dependent protein kinases (DNA-PK) play a role in the repair of double-strand DNA breaks and in the process of V(D)J recombination during lymphoid development. By EST database searching for sequences homologous to the DNA-PK gene KIP/CIB and 5-prime RACE, Seki, N et al. isolated a full-length cDNA, which they designated as KIP2, from a human fetal brain cDNA library. KIP2 encodes a deduced 187-amino acid protein with a predicted molecular mass of 22 kD. The KIP2 protein shares 46%, 39%, and 30% sequence identity with the calcium-binding proteins KIP/CIB, calcineurin B and calmodulin respectively. KIP2 contains two EF-hand motifs and a helix-loop-helix motif involved in coordinating the calcium ion, indicating that KIP2 may also bind calcium. KIP2 is ubiquitously expressed in various human tissues.

Specifications

• Antigen: KIP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CIB2
• Gene Alias: 2810434I23Rik; AI449053; calcium and integrin binding family member 2; calcium and integrin-binding family member 2; calcium binding protein Kip 2; calcium binding protein Kip2; CIB2; DFNB48; DNA-dependent protein kinase catalytic subunit-interacting protein 2; kinase interacting protein 2; kinase-interacting protein 2; KIP 2; Kip2; USH1J
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10518, 300719, 56506
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O75838, Q568Z7, Q9Z309
• Gene Symbols: CIB2
• Immunogen: A synthesized peptide derived from human CIB2(Accession O75838), corresponding to amino acid residues N40-D90.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG