Invitrogen™ Kindlin Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ 720123

Product Code. 15632105

Description

These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature. This antibody is predicted to react with Monkey, Cat and Bovine.

Kindlin 1 is a member of the kindlin family of focal adhesion proteins and contains a FERM domain and pleckstrin homology domain. It is involved in integrin signaling, linkage of the cytoskeleton to the extracellular matrix, and cell adhesion. It is most often expressed in epithelial cells. When kindlin 1 is coexpressed with talin it helps to activate ITGA2B. It is required for keratinocyte proliferation, polarization of basal keratinocytes in the skin, and for normal cell shape. Mutations in kindlin 1 have been linked to Kindler syndrome, a recessive skin disorder involving blistering, photosensitivity, poikiloderma, and atrophy.

Specifications

• Antigen: Kindlin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: FERMT1
• Gene Alias: 5830467P10Rik; C20orf42; DTGCU2; Fermitin family homolog 1; fermitin family homolog 1 (Drosophila); fermitin family member 1; FERMT1; FLJ20116; FLJ23423; KIND1; Kindlerin; kindlin 1; kindlin syndrome protein; Kindlin-1; RGD1306816; RP5-1056H1.1; UNC112 related protein 1; UNC-112 related protein 1; UNC112A; unc-112-related protein 1; URP1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55612
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2
• Gene Accession No.: Q9BQL6
• Gene Symbols: FERMT1
• Immunogen: Protein corresponding to Human FERMT1 (aa 110-320).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG