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Invitrogen™ KIDINS220 Monoclonal Antibody (P220 1F8/3)

Product Code. 11590982
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Quantity:
100 μg
Unit Size:
100µg
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11590982 100 μg 100µg
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Product Code. 11590982 Supplier Invitrogen™ Supplier No. MA190667

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Description

Mouse Monoclonal Antibody

MA1-90667 detects Kidins220 from rat samples.

This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into exons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with the onset of various neuropsychiatric disorders and neurodegenerative diseases, including Alzheimer's disease. Naturally occurring mutations in this gene are associated with a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus and obesity. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIDINS220
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone P220 1F8/3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Kidins220
Gene Accession No. Q9EQG6
Gene Alias 3110039L19Rik; AI194387; AI316525; ankyrin repeat-rich membrane spanning; ankyrin repeat-rich membrane spanning protein; ankyrin repeat-rich membrane-spanning protein; ARMS; C330002I19Rik; KIAA1250; KIDINS220; kinase D-interacting substance 220; kinase D-interacting substance of 220 kDa; kinase D-interacting substrate 220; kinase D-interacting substrate 220kDa; kinase D-interacting substrate of 220 kDa; kinase D-interacting substrate, 220kDa; MGC163482; mKIAA1250; truncated KIDINS220
Gene Symbols Kidins220
Host Species Mouse
Immunogen Recombinant Kidins220/ARMS (last 347 amino acids at the carboxy terminus) protein.
Purification Method IgG fraction
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116478
Target Species Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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