Invitrogen™ KIAA0196 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA530337

Product Code. 13484827

Description

Recommended positive controls: HeLa. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin-repeat-containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts. More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases.

Specifications

• Antigen: KIAA0196
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WASHC5
• Gene Alias: AL022848; C76463; E430025E21Rik; KIAA0196; mKIAA0196; RGD1564420; RIKEN cDNA E430025E21 gene; RTSC; RTSC1; similar to Hypothetical protein MGC31278; SPG8; Strumpellin; uncharacterized protein LOC362919; WASH complex subunit 5; WASH complex subunit strumpellin; WASHC5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9897
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q12768
• Gene Symbols: WASHC5
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Strumpellin. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG