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Ki16425, MedChemExpress

Product Code. 16475618
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Quantity:
5 mg
10 mg
50 mg
Unit Size:
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50mg
5mg
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Product Code. 16475618

Brand: Medchem Express HY13285

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Description

MedChemExpress Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK. Ki16425 can also inhibit LPA-induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells.

Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK. Ki16425 can also inhibit LPA-induced dephosphorylation of Yes-associated protein (YAP)/TAZ in HEK293A cells.

Specifications

Chemical Name or Material Ki16425
Physical Form Solid
CAS 355025-24-0
Color Off-White
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C23H23ClN2O5S
For Use With (Application) Cancer-Kinase/protease
Synonym Debio 0719
Solubility Information DMSO : ≥ 100 mg/mL (210.54 mM)
SMILES ClC1=C(C=CC=C1)C(C)OC(NC2=C(ON=C2C)C3=CC=C(C=C3)CSCCC(O)=O)=O
Molecular Weight (g/mol) 474.96
Formula Weight 474.96
Percent Purity 98.11%
Grade Research
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Research purposes only

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