Ketoconazole, Fisher BioReagents

Product Code.	Quantity	Packaging	unitSize
10430015	50 mg	Amber Glass	50mg
10754344	100 mg	Amber Glass	100mg
10032624	500 mg	Amber Glass	500mg
11448353	1 g	Amber Glass	1g

Product Code. 10430015

Brand: Fisher BioReagents BP273450

Description

Ketoconazole is a cytochrome P450 inhibitor and demonstrates anti-psoriatic activity. An antifungal agent.

Specifications

Chemical Identifiers

• CAS: 65277-42-1
• Molecular Formula: C26H28Cl2N4O4
• Molecular Weight (g/mol): 534.452
• InChI Key: XMAYWYJOQHXEEK-SIULDFEJSA-N
• Synonym: ketoconazole
• PubChem CID: 76973198
• IUPAC Name: 2,2,2-trideuterio-1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
• SMILES: CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl

• Melting Point: 148°C
• Color: White
• Ignition Residue: < 0.1%
• Loss on Drying: < 0.5%
• Melting Range: Inclusive between 148°C
• Assay Percent Range: 98%
• Packaging: Amber Glass
• Quantity: 50 mg
• Merck Index: 15, 5349
• Formula Weight: 531.44
• Physical Form: Solid
• Chemical Name or Material: Ketoconazole

Safety and Handling

Product Identifier

• Ketoconazole

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• LONG-TERM AQUATIC HAZARD Chronic 1
• ACUTE AQUATIC Acute 1
• Reproductive toxicity Category 1B
• Specific target organ toxicity after repeated exposure Category 2

Hazard Statement

• H400-Very toxic to aquatic life.
• H410-Very toxic to aquatic life with long lasting effects.
• H360F-May damage fertility.
• H373-May cause damage to organs.
• H301-Toxic if swallowed.

Precautionary Statement

• P201-Obtain special instructions before use.
• P264-Wash thoroughly after handling.
• P270-Do not eat, drink or smoke when using this product.
• P273-Avoid release to the environment.
• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P308+P313-IF exposed or concerned: Get medical advice/attention.

SDS