Invitrogen™ KEAP1 Monoclonal Antibody (7G4B10)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA517107

Product Code. 15308040

Description

MA5-17107 targets KEAP1 in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17107 immunogen is purified recombinant fragment of human KEAP1 (amino acids: 380-624 ) expressed in E. Coli. MA5-17107 detects KEAP1 which has a predicted molecular weight of approximately 69.7kDa.

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Specifications

• Antigen: KEAP1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q14145
• Gene Symbols: Keap1
• Immunogen: Purified recombinant fragment of human KEAP1 (amino acids: 380-624 ) expressed in E. Coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: 7G4B10
• Conjugate: Unconjugated
• Gene: Keap1
• Gene Alias: cytosolic inhibitor of Nrf2; INrf2; Keap1; kelch like ECH associated protein 1; Kelch-like ECH-associated protein 1; kelch-like family member 19; kelch-like protein 19; Kiaa0132; KLHL19; mKIAA0132; NRF2 cytosolic inhibitor; ring canal protein
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 9817
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid