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Invitrogen™ KDELR3 Polyclonal Antibody
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Product Code. 15980075
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100 μL
Unit Size:
100µL
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15980075 100 μL 100µL
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Product Code. 15980075 Supplier Invitrogen™ Supplier No. PA567422

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YMIYGKFRKTF DSENDTFRLE F Highest antigen sequence identity to the following orthologs - mouse 91%, rat 91%.

This gene encodes a member of the KDEL endoplasmic reticulum protein retention receptor family. Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR3 was the third member of the family to be identified. Alternate splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KDELR3
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KDELR3
Gene Accession No. O43731
Gene Alias AI173274; ER lumen protein retaining receptor 3; ER lumen protein-retaining receptor 3; ERD23; ERD2L3; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3; KDEL endoplasmic reticulum protein retention receptor 3; KDEL receptor 3; Kdelr3
Gene Symbols KDELR3
Host Species Rabbit
Immunogen Recombinant Human KDEL Receptor Pan. Recombinant protein control fragment (Product #RP-108083).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11015
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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