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Invitrogen™ KCNT2 Polyclonal Antibody

Product Code. 15760142 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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15760142 100 μL 100µL
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Product Code. 15760142 Supplier Invitrogen™ Supplier No. PA562348

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GIYRTESQKL TTSESQISIS VEEWEDTKDS KEQGHHRSNH RNSTSSDQSD HPLLRR Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

Kcnt2 calcium (Ca2+) -activated potassium channels (KCa) are a group of 6/7-TM ion channels that selectively transport K+ ions across biological membranes. KCa channels are broadly classified into three subtypes: SK, IK and BK channels (small, intermediate and big conductance). Kcnt2 is an outward rectifying potassium channel, and produces rapidly activating outward rectifier K(+) currents. Kcnt2 is activated by high intracellular sodium and chloride levels. Further, Kcnt2 channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane. Functionally, Kcnt2 is inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCNT2
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Kcnt2
Gene Accession No. Q6UVM3
Gene Alias E330038N15Rik; KCa4.2; Kcnt2; Potassium channel subfamily T member 2; potassium channel, sodium activated subfamily T, member 2; potassium channel, sodium-activated subfamily T, member 2; potassium channel, subfamily T, member 2; potassium sodium-activated channel subfamily T member 2; sequence like an intermediate conductance potassium channel subunit; SLICK; SLO2.1; sodium- and chloride-activated ATP-sensitive potassium channel; sodium and chloride-activated ATP-sensitive potassium channel Slo2.1; sodium- and chloride-activated ATP-sensitive potassium channel subunit; sodium-and chloride-activated ATP-sensitive potassium channel (SLICK)
Gene Symbols Kcnt2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human KCNT2. Recombinant protein control fragment (Product #RP-101419).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 343450
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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