Invitrogen™ KCNS3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596856

Product Code. 16559691

Description

Immunogen sequence: MVFGEFFHRP GQDEELVNLN VGGFKQSVDQ STLLRFPHTR LGKLLTCHSE EAILELCDDY SVADKEYYFD RNPSLFRYVL NFYYTGKLHV MEELCVFSFC QEIEYWGINE LFIDSCCSNR YQERKEENHE KDWDQKSHDV STDSSFEESS LFEKELEKFD TLRFGQLRKK IWIRMENPAY; Positive Samples: A-549, SGC-7901, HT-29, Mouse brain, Rat brain; Cellular Location: Cell membrane, Multi-pass membrane protein.

Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: KCNS3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNS3
• Gene Alias: Delayed-rectifier K(+) channel alpha subunit 3; Kcns3; KV9.3; potassium voltage-gated channel delayed-rectifier protein S3; potassium voltage-gated channel modifier subfamily S member 3; potassium voltage-gated channel subfamily S member 3; potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3; potassium voltage-gated channel, modifier subfamily S, member 3; Shab-related delayed-rectifier K+ channel (Kv9.3); Shab-related delayed-rectifier K+ channel alpha subunit 3; voltage-gated potassium channel protein Kv9.3; voltage-gated potassium channel subunit Kv9.3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 238076, 3790, 83588
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.27 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O88759, Q8BQZ8, Q9BQ31
• Gene Symbols: KCNS3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human KCNS3 (NP_0022433).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG