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Invitrogen™ KCNQ5 Polyclonal Antibody
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Product Code. 30019532
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Quantity:
100 μL
Unit Size:
100µL
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30019532 100 μL 100µL
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Product Code. 30019532 Supplier Invitrogen™ Supplier No. PA5144594

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Description

Rabbit Polyclonal Antibody

KCNQ5 Polyclonal Antibody for Western Blot

KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KNCQs (KCNQ1-5) found in the central nervous system. Studies have shown that KCNQ3 and KCNQ5 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy. Voltage-dependent potassium channels are key regulators of the resting membrane potential and modulate the excitability of electrically active cells. The channels are usually tetrameric and can interact with auxiliary subunits that enhance or modify currents mediated by the pore-forming subunits.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCNQ5
Applications Western Blot
Classification Polyclonal
Concentration 0.45 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal
Gene KCNQ5
Gene Accession No. Q9NR82
Gene Alias 7730402H11; 9230107O05Rik; AA589396; D1Mgi1; KCNQ5; Kcnq5l; KQT-like 5; Kv7.5; KvLQT5; potassium channel protein; potassium channel subunit alpha KvLQT5; potassium channel, voltage gated KQT-like subfamily Q, member 5; potassium channel, voltage-gated KQT-like subfamily Q, member 5; potassium voltage-gated channel subfamily KQT member 5; potassium voltage-gated channel subfamily Q member 5; potassium voltage-gated channel, KQT-like subfamily, member 5; potassium voltage-gated channel, subfamily Q, member 5; rCG_43583; voltage-gated potassium channel subunit Kv7.5; voltage-gated potassium channel type Kv7.5
Gene Symbols KCNQ5
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human KCNQ5. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56479
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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