KCNQ3 Rabbit anti-Human, Porcine, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16899444	Proteintech 19966-1-AP-20UL	20 μL
16889444	Proteintech 19966-1-AP-150UL	150 μL

Description

The antibody recognizes the C-term of KCNQ3.

KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KCNQs (KCNQ1-5) found in the central nervous system and KCNQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.

Specifications

• Antigen: KCNQ3
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Pig
• Gene Accession No.: O43525
• Gene ID (Entrez): 100157152, 3786
• Immunogen: Peptide
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: KCNQ3

• Concentration: 0.13 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: BFNC2, EBN2, KCNQ3, KQT like 3, KV7.3
• Gene Symbols: KCNQ3
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody