Invitrogen™ KCNMB4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA550692

Product Code. 15604625

Description

The antibody detects endogenous levels of total KCNMB4 protein.

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.

Specifications

• Antigen: KCNMB4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNMB4
• Gene Alias: 1700058G18Rik; 2900045G12Rik; big potassium channel beta subunit 4; BK channel beta subunit 4; BK channel subunit beta-4; BKbeta4; calcium activated potassium channel beta 4 subunit; calcium-activated potassium channel subunit beta-4; Calcium-activated potassium channel, subfamily M subunit beta-4; charybdotoxin receptor subunit beta-4; hbeta4; k(VCA)beta-4; KCMB4; KCNMB4; large conductance calcium-dependent potassium ion channel beta 4 subunit; maxi K channel subunit beta-4; MaxiK channel beta-subunit 4; potassium calcium-activated channel subfamily M regulatory beta subunit 4; potassium channel subfamily M regulatory beta subunit 4; potassium large conductance calcium-activated channel, subfamily M, beta member 4; slo-beta-4; Slowpoke beta 4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27345, 58802
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2.9 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q86W47, Q9JIN6
• Gene Symbols: KCNMB4
• Immunogen: Synthetic peptide corresponding to residues near the N terminal of human potassium large conductance calcium-activated channel, subfamily M, beta member 4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG