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Invitrogen™ KCNK18 Polyclonal Antibody

Product Code. 12839022
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12839022 100 μg 100µg
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Product Code. 12839022 Supplier Invitrogen™ Supplier No. PA520873

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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat brain tissue lysate. PA5-20873 can be used with blocking peptide PEP-0987.

TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KCNK18
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene KCNK18
Gene Accession No. Q6Q1P3, Q6VV64, Q7Z418
Gene Alias 2P K ion channel TRESK; Gm781; K2p18.1; Kcnk18; MGR13; Potassium channel subfamily K member 18; potassium channel, subfamily K, member 18; potassium channel, two pore domain subfamily K, member 18; potassium two pore domain channel subfamily K member 18; tandem-pore K+ (K(2P)) channel; Tresk; TRESK2; Tresk-2; TRIK; TWIK-related individual K+ channel; TWIK-related individual potassium channel; TWIK-related spinal cord K+ channel; TWIK-related spinal cord potassium channel; Two-pore-domain potassium channel TRESK
Gene Symbols KCNK18
Host Species Rabbit
Immunogen A 17 amino acid peptide from near the center of human TRESK.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 332396, 338567, 445371
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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