Invitrogen™ KChIP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ 720416

Artikelnummer. 15904114

Beschreibung

This antibody is predicted to react with Monkey, Bovine, Cat.

Voltage-gated potassium (Kv) channels are key components of the potassium currents in the heart and central nervous system. In the heart, Kv4 channels are involved in the repolarization phase of the action potential. In the brain however, these channels prevent reverse-propagation of action potentials. Found associated with Kv4 channels are a group of calcium-binding proteins termed KChIPs (Kv channel interacting proteins). KChIPs are small molecular weight proteins that bind to the cytoplasmic amino termini of Kv4 alpha-subunits and help to modulate its function. There are currently three known KChIPs; KChIP1 expressed in the brain; KChIP2 expressed in the brain, heart, and lung, and has three isoforms, a, b, and c; and KChIP3, also known as calsenilin and DREAM (downstream regulatory elements (DRE)-antagonist modulator) which is expressed in the brain and testis.

Spezifikation

• Antigen: KChIP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNIP2
• Gene Alias: A-type potassium channel modulatory protein 2; Cardiac voltage-gated potassium channel modulatory subunit; DKFZp566L1246; KCHIP2; KChlP2; Kcnip2; Kv channel interacting protein 2; Kv channel-interacting protein; Kv channel-interacting protein 2; MGC17241; potassium channel auxiliary subunit KCHIP2; potassium channel-interacting protein 2; potassium voltage-gated channel interacting protein 2; si:ch73-173h19.2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 30819
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q9NS61
• Gene Symbols: KCNIP2
• Immunogen: Peptides corresponding to human KCNIP2 [1) aa14-aa33 2) aa65-aa82].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG