Invitrogen™ KARS Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA559524

Product Code. 15727381

Description

Immunogen sequence: GMVKHITGSY KVTYHPDGPE GQAYDVDFTP PFRRINMVEE LEKALGMKLP ETNLFETEET RKILDDICVA KAVECPPPRT TARLLDKLVG EFLEVTCINP TFICDHPQIM SPLAKWHRSK Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 90%.

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: KARS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KARS1
• Gene Alias: AA589550; AL024334; AL033315; AL033367; CMTRIB; D8Ertd698e; D8Wsu108e; DFNB89; EC 6.1.1.6; KARS; Kars1; KARS2; KIAA0070; KRS; lysine tRNA ligase; lysine--tRNA ligase; LysRS; lysyl-tRNA synthetase; mKIAA0070
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 292028, 3735, 85305
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q15046, Q5XIM7, Q99MN1
• Gene Symbols: KARS1
• Immunogen: Recombinant protein corresponding to Human KARS. Recombinant protein control fragment (Product #RP-98536).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG