Invitrogen™ KARS Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA589426

Product Code. 16557331

Description

Immunogen sequence: IAPELYHKML VVGGIDRVYE IGRQFRNEGI DLTHNPEFTT CEFYMAYADY HDLMEITEKM VSGMVKHITG SYKVTYHPDG PEGQAYDVDF TPPFRRINMV EELEKALGMK LPETNLFETE ETRKILDDIC VAKAVECPPP RTTARLLDKL VGEFLEVTCI NPTFICDHPQ IMSPLAKWHR SKEGLTERFE LFVMKKEICN AYTELNDPMR QRQLFEEQAK AKAAGDDEAM FIDENFCTAL EYGLPPTAGW GMGIDRVAMF LTDSNNIKEV LLFPAMKPED KKENVATTDT LESTTVGTSV; Positive Samples: HepG2, Jurkat, HeLa, 293T, Mouse heart, Mouse kidney, Rat liver; Cellular Location: Cell membrane, Cytoplasm, Mitochondrion, Nucleus, Peripheral membrane protein.

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: KARS
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KARS1
• Gene Alias: AA589550; AL024334; AL033315; AL033367; CMTRIB; D8Ertd698e; D8Wsu108e; DFNB89; EC 6.1.1.6; KARS; Kars1; KARS2; KIAA0070; KRS; lysine tRNA ligase; lysine--tRNA ligase; LysRS; lysyl-tRNA synthetase; mKIAA0070
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 292028, 3735, 85305
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 3.14 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q15046, Q5XIM7, Q99MN1
• Gene Symbols: KARS1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 298-597 of human LysRS/LysRS/KARS (NP_0055391).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG