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Kappa Light Chain Antibody (L1C1), Novus Biologicals™

Product Code. 18405062 Shop All Bio Techne Products
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20 ug
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20µg
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18405062 20 ug 20µg
18104805 0.1 mg 0.1mg
18116372 0.2 mg 0.2mg
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Product Code. 18405062 Supplier Novus Biologicals Supplier No. NBP21519120ug

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Description

Mouse Monoclonal Antibody

Kappa Light Chain Monoclonal specifically detects Kappa Light Chain in Human samples. It is validated for Western Blot, Simple Western, Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Kappa Light Chain
Classification Monoclonal
Clone L1C1
Concentration 0.2mg/mL
Conjugate Unconjugated
Dilution Western Blot 0.5-1ug/ml, Simple Western 10 ug/ml, Flow Cytometry 0.5-2ug/million cells, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, SDS-Page
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. P01601
Gene Alias HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809
Gene Symbols IGKC
Host Species Mouse
Immunogen B lymphoma cells
Molecular Weight of Antigen 22.5 kDa
Purification Method Protein G purified
Quantity 20 ug
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3514
Test Specificity This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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