Invitrogen™ KAP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA554878

Product Code. 15702811

Description

Immunogen sequence: ELLNAQQEDD EFVCQIIYVF YQMVFHQATR DVIIKETQAP AYLIDLMHDK NNEIRKVCDN TLDIIAEYDE EWAKK Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: KAP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KIFAP3
• Gene Alias: dJ190I16.1; FLA3; KAP-1; KAP3; KAP-3; KIF3AP; Kifap3; kinesin associated protein 3; kinesin-associated protein 3; small G protein GDP dissociation stimulator; SMAP; Smg GDS-associated protein; Smg-GDS
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22920
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q92845
• Gene Symbols: KIFAP3
• Immunogen: Recombinant protein corresponding to Human KAP3. Recombinant protein control fragment (Product #RP-94021).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG