Kanamycin monosulfate

Product Code.	Quantity	Unit Size
15473879	10 g	10g
15483879	25 g	25g
15493879	100 g	100g

Product Code. 15473879 Supplier Thermo Scientific Alfa Aesar Supplier No. J61272.09

Description

Kanamycin monosulfate, CAS # 25389-94-0, is an aminoglycoside sulfate salt with antibacterial activity. | CAS: 25389-94-0 | C18H38N4O15S | 582.575 g/mol

Antibiotic. Inhibits translocation during protein biosynthesis.Kanamycin monosulfate acts as an antibiotic and used to treat various infections. It is involved in the translation of prokaryotic ribosomes arises due to bacterial cell death. It is used as a selective agent in molecular biology in order to isolate transformants that are expressing a kanamycin resistance gene.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Kanamycin monosulfate is the sulfate salt form of kanamycin A
• It was isolated from Streptomyces kanamyceticus
• This compound inhibits translocation during protein biosynthesis. It binds to the 30S ribosomal subunit, causing misreading of the mRNA sequence

Application

• Kanamycin monosulfate shows antibacterial activity. It is effective against gram-positive and gram-negative bacteria, as well as Mycoplasma species
• This compound is also involved in translating prokaryotic ribosomes
• In molecular biology experiments, it is commonly used to select and isolate transformants expressing the kanamycin resistance gene, and plants that have the NPT II (APH3) gene incorporated

Specifications

Chemical Identifiers

• CAS: 25389-94-0
• Molecular Formula: C18H38N4O15S
• Molecular Weight (g/mol): 582.575
• MDL Number: MFCD00070253
• InChI Key: OOYGSFOGFJDDHP-IZQIRFRQSA-N
• Synonym: Kanamycin A
• PubChem CID: 134129479
• IUPAC Name: (2R,3S,4S,5S,6R)-2-(aminomethyl)-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
• SMILES: C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O

• Type: Kanamycin Monosulfate
• Physical Form: Powder
• Color: White
• Quantity: 10 g
• Merck Index: 14,5281
• Solubility Information: Dissolve in water at 10mg/ml.Soluble in water.
• Formula Weight: 582.58
• Chemical Name or Material: Kanamycin monosulfate

Safety and Handling

Product Identifier

• Kanamycin monosulphate

Signal Word

• Danger

Hazard Category

• Reproductive toxicity Category 1B
• Respiratory sensitiser Category 1
• Skin sensitiser Category 1

Hazard Statement

• H317-May cause an allergic skin reaction.
• H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
• H360FD-May damage fertility. May damage the unborn child.

Precautionary Statement

• P201-Obtain special instructions before use.
• P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P308+P313-IF exposed or concerned: Get medical advice/attention.
• P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .

Supplemental information

• MIXTURE LIST-Contain: Kanamycin sulphate

SDS

RUO – Research Use Only