Invitrogen™ Kallikrein 6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA588324

Product Code. 16546601

Description

Immunogen sequence: AASHDQDIML LRLARPAKLS ELIQPLPLER DCSANTTSCH ILGWGKTADG DFPDTIQCAY IHLVSREECE HAYPGQITQN MLCAGDEKYG KDSCQGDSGG PLVCGDHLRG LVSWGNIPCG SKEKPGVYTN VCRYTNWIQK TIQAK; Positive Samples: HT-29; Cellular Location: Cytoplasm, Microsome, Mitochondrion, Nucleus, nucleolus.

Kallikreins, including Kallikrein 6, are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.

Specifications

• Antigen: Kallikrein 6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Klk6
• Gene Alias: 0610007D04Rik; AI849898; brain serine protease; BSP; Bssp; Glandular kallikrein K1; hK6; Kal; KAL-B; kallikrein 1; kallikrein 29; kallikrein 6; kallikrein 6 (neurosin); kallikrein 6 (neurosin, zyme); kallikrein 7; kallikrein related peptidase 6; kallikrein related-peptidase 6; kallikrein renal/pancreas/salivary; kallikrein-1; Kallikrein6; Kallikrein-6; Klk1; Klk1b6; Klk29; Klk6; Klk-6; Klk7; MGC9355; mGK-6; MSP; myelencephalon-specific protease; myofibril-bound protease; neurosin; Protease M; protease serine 9 (neurosin); protease, serine, 18; protease, serine, 9; PRSS18; PRSS9; renal kallikrein; Serine protease 18; serine protease 9; SP59; tissue kallikrein-6; true tissue kallikrein; zyme
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5653
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.57 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q92876
• Gene Symbols: Klk6
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human KLK6 (NP_0027651).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG