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Invitrogen™ KAL1 Polyclonal Antibody

Product Code. 12849292
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Quantity:
100 μg
Unit Size:
100µg
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12849292 100 μg 100µg
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Product Code. 12849292 Supplier Invitrogen™ Supplier No. PA521149

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Description

Rabbit Polyclonal Antibody

A suggested positive control is MCF7 cell lysate. PA5-21149 can be used with blocking peptide PEP-1263.

KAL1 (Anosmin-1) an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KAL1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ANOS1
Gene Accession No. P23352
Gene Alias Adhesion molecule-like X-linked; ADMLX; ANOS1; anosmin; anosmin 1; Anosmin1; anosmin-1; HH1; HHA; KAL; KAL1; KALIG1; KALIG-1; Kallmann syndrome interval gene 1; kallmann syndrome protein; Kallmann syndrome-1 sequence (anosmin-1); KMS; WAP four-disulfide core domain 19; WFDC19
Gene Symbols ANOS1
Host Species Rabbit
Immunogen An 18 amino acid peptide near the center of human Anosmin.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3730
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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