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Tocris Bioscience™ JZL 184
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Product Code. 18065312
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18065312

Brand: Tocris Bioscience™ 3836/50

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This item is not returnable. View return policy

Description

Potent MAGL inhibitor

Potent and selective MAGL inhibitor. Blocks hydrolysis of the endocannabinoid 2-arachidonyl glycerol (2-AG) in vivo in the mouse brain (IC50 = 8 nM). Potentiates depolarization-induced suppression of excitability in cerebellar Purkinje neurons. Exhibits >300-fold selectivity for MAGL over FAAH in vitro. Attenuates nociception in neuropathic and inflammatory pain models. Also reduces free fatty acid levels in primary tumors.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1101854-58-3
Molecular Formula C27H24N2O9

Specifications

Quantity 50 mg
Formula Weight 520.49
Purity >98%
Molecular Weight (g/mol) 520.494
Chemical Name or Material JZL 184
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