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JZL 184, MedChemExpress

Product Code. 16486686
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Product Code. 16486686 Supplier Medchem Express Supplier No. HY15249

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Description

MedChemExpress JZL 184 is a potent, selective and irreversible MAGL inhibitor that blocks 2-Arachidonoylglycerol (2-AG) hydrolysis in brain membranes (IC50 of 8 nM). JZL 184 displays >300-fold selectivity for MAGL over FAAH.

JZL 184 is a potent, selective and irreversible MAGL inhibitor that blocks 2-Arachidonoylglycerol (2-AG) hydrolysis in brain membranes (IC50 of 8 nM). JZL 184 displays >300-fold selectivity for MAGL over FAAH.

Specifications

Chemical Name or Material JZL 184
CAS 1101854-58-3
Color Off-White
Purity Grade Notes Research
Molecular Formula C27H24N2O9
Quantity 100 mg
Solubility Information DMSO : ≥ 35 mg/mL (67.24 mM)
SMILES OC(C1=CC=C(OCO2)C2=C1)(C3CCN(C(OC4=CC=C([N+]([O-])=O)C=C4)=O)CC3)C5=CC(OCO6)=C6C=C5
Molecular Weight (g/mol) 520.49
Formula Weight 520.49
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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