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JQ-1 (carboxylic acid), MedChemExpress

Product Code. 16491956
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Product Code. 16491956

Brand: Medchem Express HY78695

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Description

MedChemExpress JQ-1 carboxylic acid, a type of (+)-JQ-1 derivative, is a potent BET bromodomain inhibitor for downregulating PD-L1 expression on the surface of tumor cells. JQ-1 carboxylic acid can be used as a precursor to synthesize PROTACs, which targets BET bromodomains.

JQ-1 carboxylic acid, a type of (+)-JQ-1 derivative, is a potent BET bromodomain inhibitor for downregulating PD-L1 expression on the surface of tumor cells. JQ-1 carboxylic acid can be used as a precursor to synthesize PROTACs, which targets BET bromodomains.

Specifications

Chemical Name or Material JQ-1 (carboxylic acid)
Physical Form Powder
CAS 202592-23-2
Color Yellow
Quantity 500 mg
Purity Grade Notes Research
Molecular Formula C19H17ClN4O2S
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : 31.25 mg/mL (77.95 mM; ultrasonic and warming and heat to 60°C)
SMILES ClC1=CC=C(C(C2=C(N3C4=NN=C3C)SC(C)=C2C)=N[C@H]4CC(O)=O)C=C1
Molecular Weight (g/mol) 400.88
Formula Weight 400.88
Percent Purity 98.01%
Grade Research
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Research purposes only

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