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Invitrogen™ JMJD2C Recombinant Rabbit Monoclonal Antibody (23H4L4)

Product Code. 16391784
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Quantity:
100 μg
Unit Size:
100µg
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16391784 100 μg 100µg
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Product Code. 16391784 Supplier Invitrogen™ Supplier No. 703380

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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Pig, Cat, Sheep. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3; thereby, playing a central role in histone code. KDM4C does not demethylate histone H3 'Lys-4', H3 'Lys-27', or H4 'Lys-20'. It demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residues. There is no activity on mono- or dimethylated residues. Demethylation of Lys residues generates formaldehyde and succinate.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JMJD2C
Applications Western Blot
Classification Recombinant Monoclonal
Clone 23H4L4
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene KDM4C
Gene Accession No. Q9H3R0
Gene Alias 2410141F18Rik; AA517467; bA146B14.1; GASC1; GASC-1 protein; gene amplified in squamous cell carcinoma 1; gene amplified in squamous cell carcinoma 1 protein; JHDM3C; JmjC domain-containing histone demethylation protein 3C; JMJD2C; jumonji domain containing 2C; jumonji domain-containing protein 2C; Kdm4c; KIAA0780; lysine (K)-specific demethylase 4C; lysine demethylase 4C; lysine-specific demethylase 4C; RP11-169L18.1; TDRD14C; tudor domain containing 14C
Gene Symbols KDM4C
Host Species Rabbit
Immunogen Peptides corresponding to human KDM4C [1) aa1019-aa1038 2) aa494-aa513].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23081
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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