Invitrogen™ JMJD2C Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5115461

Product Code. 17238243

Description

Antibody detects endogenous levels of total KDM4C / GASC1 / JMJD2C.

Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3; thereby, playing a central role in histone code. KDM4C does not demethylate histone H3 'Lys-4', H3 'Lys-27', or H4 'Lys-20'. It demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residues. There is no activity on mono- or dimethylated residues. Demethylation of Lys residues generates formaldehyde and succinate.

Specifications

• Antigen: JMJD2C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KDM4C
• Gene Alias: 2410141F18Rik; AA517467; bA146B14.1; GASC1; GASC-1 protein; gene amplified in squamous cell carcinoma 1; gene amplified in squamous cell carcinoma 1 protein; JHDM3C; JmjC domain-containing histone demethylation protein 3C; JMJD2C; jumonji domain containing 2C; jumonji domain-containing protein 2C; Kdm4c; KIAA0780; lysine (K)-specific demethylase 4C; lysine demethylase 4C; lysine-specific demethylase 4C; RP11-169L18.1; TDRD14C; tudor domain containing 14C
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23081, 298144, 76804
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q8VCD7, Q9H3R0
• Gene Symbols: KDM4C
• Immunogen: A synthesized peptide derived from human KDM4C(Accession Q9H3R0), corresponding to amino acid residues Y472-G522.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG