Invitrogen™ JIP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529245

Product Code. 13483377

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse brain. Predicted reactivity: Mouse (98%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.

Specifications

• Antigen: JIP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MAPK8IP2
• Gene Alias: 3230402N03Rik; AI847694; AW049958; C-Jun-amino-terminal kinase-interacting protein 2; homologous to mouse JIP-1; IB 2; Ib2; IB-2; Islet brain 2; islet-brain 2; islet-brain-2; JIP 2; JIP2; JIP-2; JNK MAP kinase scaffold protein 2; JNK MAP kinase scaffold protein JIP2; JNK-interacting protein 2; Mapk8ip2; mitogen activated protein kinase 8 interacting protein 2; mitogen-activated protein kinase 8 interacting protein 2; mitogen-activated protein kinase 8-interacting protein 2; PRKM8IPL; R75148; si:dkey-180h12.2; si:dkey-181m21.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23542, 60597
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q13387, Q9ERE9
• Gene Symbols: MAPK8IP2
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human JIP2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG