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JI051, MedChemExpress

Product Code. 16485646
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Product Code. 16485646 Supplier Medchem Express Supplier No. HY117113

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MedChemExpress JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity.

JI051 is a stabilizer for the Hes1-PHB2 interaction. JI051 interacts with a cancer-associated protein chaperone prohibitin 2 (PHB2), induces cell-cycle arrest by inhibiting the Notch downstream effector gene Hes1. Anti-cancer activity.

Specifications

Chemical Name or Material JI051
CAS 2234281-75-3
Color Yellow
Purity Grade Notes Research
Molecular Formula C22H24N2O3
Quantity 100 mg
Solubility Information DMSO : 125 mg/mL (342.99 mM; Need ultrasonic)
SMILES O=C(NCCC1=CC=CC=C1OCC)/C=C/C2=CNC3=C2C=CC=C3OC
Molecular Weight (g/mol) 364.44
Formula Weight 364.44
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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