missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 18796668

Tocris Bioscience™ JH 295
GREENER_CHOICE

Product Code. 18796668
Click to view available options
Quantity:
2 mg
Unit Size:
2mg
This item is not returnable. View return policy

Product Code. 18796668

Brand: Tocris Bioscience™ 4322/2

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Irreversible Nek2 inhibitor

JH 295 is an irreversible Nek2 inhibitor (IC50=770 nM). Inhibits Nek2 via alkylation of residue Cys22. Displays 5-fold selectivity for Nek2 over Cdk1. Exhibits no significant effect on Aurora B or Plk1 kinases, bipolar spindle assembly or spindle assembly checkpoint. Cell permeable.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-[(3Z)-3-[(2-Ethyl-4-methyl-1H-imidazol-5-yl)methylene]-2,3-dihydro-2-oxo-1H-indol-5-yl]-2-propynamide
CAS 1311143-71-1
Assay Percent Range >98%
Quantity 2 mg
Molecular Formula C18H16N4O2
Formula Weight Observed MW: 320.35
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.