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JG-98, MedChemExpress

Product Code. 16451127
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Product Code. 16451127 Supplier Medchem Express Supplier No. HY117282

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Description

MedChemExpress JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages.

JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction. JG-98 shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages.

Specifications

Chemical Name or Material JG-98
Physical Form Solid
CAS 1456551-16-8
Color Orange
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C24H21Cl2N3OS3
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : 5 mg/mL (9.35 mM; Need ultrasonic)
SMILES CN1/C(SC2=CC(Cl)=CC=C12)=C3S/C(N(CC)C\3=O)=C\C4=[N+](C=CS4)CC5=CC=CC=C5.[Cl-]
Molecular Weight (g/mol) 534.54
Formula Weight 534.54
Percent Purity 99.75%
Grade Research
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Research purposes only

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