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JAK3-IN-1, MedChemExpress

Product Code. 16453757
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Product Code. 16453757

Brand: Medchem Express HY19544

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Description

MedChemExpress JAK3-IN-1 is a potent, selective and orally active JAK3 inhibitor with an IC50 of 4.8 nM. JAK3-IN-1 shows over 180-fold more selective for JAK3 than JAK1 (IC50 of 896 nM) and JAK2 (IC50 of 1050 nM).

JAK3-IN-1 is a potent, selective and orally active JAK3 inhibitor with an IC50 of 4.8 nM. JAK3-IN-1 shows over 180-fold more selective for JAK3 than JAK1 (IC50 of 896 nM) and JAK2 (IC50 of 1050 nM).

Specifications

Chemical Name or Material JAK3-IN-1
CAS 1805787-93-2
Color White
Purity Grade Notes Research
Molecular Formula C26H30ClN7O2
Quantity 50 mg
Solubility Information DMSO : 100 mg/mL (196.84 mM; Need ultrasonic)
SMILES O=C(C=C)NC1=CC(CNC2=NC(NC3=C(OC)C=C(N4CCN(C)CC4)C=C3)=NC=C2Cl)=CC=C1
Molecular Weight (g/mol) 508.02
Formula Weight 508.02
Percent Purity 99.23%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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