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Invitrogen™ J Chain Polyclonal Antibody

Product Code. 16320665
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Quantity:
100 μL
Unit Size:
100µL
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16320665 100 μL 100µL
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Product Code. 16320665 Supplier Invitrogen™ Supplier No. PA583707

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VDNKCKCARI TSRIIRSSED PNEDIVERNI RIIVPLNNRE NISDPTSPLR TRFVYHLSDL CKKCDPTEVE LDNQIVTATQ SNICDEDSAT ETCYTYDRNK CYTAVVPLVY GGETKMVETA Highest antigen sequence indentity to the following orthologs: Mouse - 79%, Rat - 80%.

J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.
TRUSTED_SUSTAINABILITY

Specifications

Antigen J Chain
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene JCHAIN
Gene Accession No. P01591
Gene Alias 9530090F24Rik; AI323815; IGCJ; Igj; IgJ chain; immunoglobulin J chain; immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides; immunoglobulin joining chain; immunoglobulin joining gene (not J region); J chain; Jch; JCHAIN; Joining chain of multimeric IgA and IgM
Gene Symbols JCHAIN
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human JCHAIN. Recombinant protein control fragment (Product #RP-102957).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3512
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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