Itraconazole, MedChemExpress

Product Code.	Quantity	unitSize
16461876	500 mg	500mg
16407356	100 mg	100mg

Artikelnummer. 16461876 Lieferant Medchem Express Lieferanten-Nr. HY17514

Beschreibung

MedChemExpress Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ∼800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor.

Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ∼800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein (OSBP) inhibitor.

Spezifikation

• Chemical Name or Material: Itraconazole
• Physical Form: Solid
• CAS: 84625-61-6
• Color: White
• Quantity: 500 mg
• Purity Grade Notes: Research
• Molecular Formula: C₃₅H₃₈Cl₂N₈O₄
• For Use With (Application): COVID-19-immunoregulation
• Synonym: R51211
• Solubility Information: DMSO : 6.25 mg/mL (8.86 mM; Need ultrasonic)
• SMILES: ClC1=C(C=CC(Cl)=C1)[C@@]2(O[C@@H](COC3=CC=C(N4CCN(C5=CC=C(N(C=NN6C(C)CC)C6=O)C=C5)CC4)C=C3)CO2)CN7C=NC=N7
• Molecular Weight (g/mol): 705.63
• Formula Weight: 705.63
• Percent Purity: 99.15%
• Grade: Research

Research purposes only