Invitrogen™ ITPR3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552021

Product Code. 15789970

Description

Immunogen sequence: ITSTKNEKIF QESIGLAIHL LDGGNTEIQK SFHNLMMSDK KSERFFKVLH DRMKRAQQET KSTVAVNMND LGSQPHEDRE PVDPTTKGRV ASFSIPGSSS RYSLGPSLRR GHEVSERVQS SEMGTSVLIM QPILRFLQLL CENHNRD Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 89%.

This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.

Specifications

• Antigen: ITPR3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ITPR3
• Gene Alias: inositol 1,4,5-triphosphate receptor 3; inositol 1,4,5-triphosphate receptor, type 3; inositol 1,4,5-trisphosphate receptor type 3; inositol 1,4,5-trisphosphate receptor, type 3; insP3R3; IP3 receptor; IP3 receptor isoform 3; IP3R; IP3R 3; Ip3r3; IP3R-3; IP3R3X; ITPR3; Itpr-3; Type 3 inositol 1,4,5-trisphosphate receptor; type 3 InsP3 receptor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3710
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q14573
• Gene Symbols: ITPR3
• Immunogen: Recombinant protein corresponding to Human ITPR3. Recombinant protein control fragment (Product #RP-102275).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG