ITM2C Mouse anti-Human, Clone: 2E8G11, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 60095-1-IG-150UL

Product Code. 16867065

Description

Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.

Specifications

• Antigen: ITM2C
• Classification: Monoclonal
• Concentration: 0.95 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q9NQX7
• Gene Symbols: ITM2C
• Immunogen: ITM2C Fusion Protein Ag4409
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: 2E8G11
• Conjugate: Unconjugated
• Gene: ITM2C
• Gene Alias: BRICD2C, Cerebral protein 14, E25, E25C, integral membrane protein 2C, ITM2C, ITM3, PSEC0047, Transmembrane protein BRI3
• Host Species: Mouse
• Purification Method: Caprylic Acid Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 81618
• Content And Storage: -20°C
• Form: Liquid