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Invitrogen™ ITK Monoclonal Antibody (5G6)

Product Code. 12827902
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
12827902 100 μL 100µL
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Product Code. 12827902 Supplier Invitrogen™ Supplier No. MA515879

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Description

Mouse Monoclonal Antibody

MA5-15879 targets ITK in indirect ELISA, flow cytometry, Western blot, and immunofluorescence applications and shows reactivity with Human samples. The MA5-15879 immunogen is purified recombinant fragment of human ITK expressed in E. Coli. . MA5-15879 detects ITK which has a predicted molecular weight of approximately 72kDa.

ITK is a tyrosine kinase expressed in T-cells which contains both SH2 and SH3 domains. ITK is thought to play a role in T-cell proliferation and differentiation. The Tec family of non-receptor tyrosine kinases is composed of six proteins designated Tec, Itk (also known as Emt or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain pleckstrin homology (PH) and Tec homology (TH) domains in their amino termini. Itk associates with CD28 and becomes activated subsequent to CD28 ligation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ITK
Applications ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 5G6
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene ITK
Gene Accession No. Q08881
Gene Alias EMT; homolog of mouse T-cell itk/tsk; IL2 inducible T cell kinase; IL2 inducible T-cell kinase; IL-2-inducible T cell kinase; IL-2-inducible T-cell kinase; IL2-inducible T-cell kinase; interleukin-2-inducible T cell kinase; interleukin-2-inducible T-cell kinase; ITK; Kinase EMT; kinase TLK; LPFS1; LYK; MGC126257; MGC126258; PSCTK2; T-cell-specific kinase; Tcsk; Tlk; Tsk; Tyrosine-protein kinase ITK/TSK; tyrosine-protein kinase LYK
Gene Symbols ITK
Host Species Mouse
Immunogen Purified recombinant fragment of human ITK expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3702
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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