ITIH2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA11756

Product Code. 11501872

Description

PA1-1756 detects HC2 from human and mouse samples. PA1-1756 has been successfully used in immunohistochemical staining of paraffin embedded tissue sections. The PA1-1756 immunogen is a synthetic peptide corresponding to residues E A N N L G L L D P N. This immunizing peptide (PEP-302) is available for neutralization and control experiments.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: ITIH2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ITIH2
• Gene Alias: PSMA1, proteasome (prosome, macropain) subunit, alpha type, 1, 30 kDa prosomal protein, Macropain subunit C2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16425, 3698
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: P19823, Q61703
• Gene Symbols: ITIH2
• Immunogen: Synthetic peptide corresponding to residues E A N N L G L L D P N.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG