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ITI-214 free base, MedChemExpress

Product Code. 16481427
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50 mg
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50mg
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Product Code. 16481427

Brand: Medchem Express HY12501

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Description

MedChemExpress ITI-214 free base is a potent, CNS-active, orally bioavailable PDE1 inhibitor (Ki of 58 pM) with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters and ion channels.

ITI-214 free base inhibits recombinant full-length human PDE1A, PDE1B and PDE1C with Kis of 33 pM, 380 pM and 35 pM, respectively. ITI-214 free base shows efficacy in various animal models of motor and cognitive functions.

Specifications

Chemical Name or Material ITI-214 free base
CAS 1160521-50-5
Color Off-White
Purity Grade Notes Research
Molecular Formula C29H26FN7O
Quantity 50 mg
SMILES O=C(C1=C(NC2=CC=CC=C2)N(CC3=CC=C(C4=NC(F)=CC=C4)C=C3)N=C1N56)N(C)C5=N[C@@]7([H])[C@]6([H])CCC7
Molecular Weight (g/mol) 507.56
Formula Weight 507.56
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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