Invitrogen™ ISCU Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA530470

Product Code. 13444967

Description

Recommended positive controls: U87-MG, SK-N-SH, IMR32, SK-N-AS, ISCU-transfected 293T. Predicted reactivity: Mouse (97%), Rat (97%), Drosophila (84%), Rhesus Monkey (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.

Specifications

• Antigen: ISCU
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ISCU
• Gene Alias: 2310020H20Rik; AA407971; HML; hnifU; iron-sulfur cluster assembly enzyme; iron-sulfur cluster assembly enzyme ISCU, mitochondrial; iron-sulfur cluster scaffold homolog; Iscu; IscU iron-sulfur cluster scaffold homolog; IscU iron-sulfur cluster scaffold homolog (E. coli); ISCU2; ISU2; Nifu; NifU-like N-terminal domain containing; nifU-like N-terminal domain-containing protein; NifU-like protein; NIFUN; RGD1309562
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23479, 66383
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.66 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q9D7P6, Q9H1K1
• Gene Symbols: ISCU
• Immunogen: Recombinant protein encompassing a sequence within the center region of human ISCU. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG