Irinotecan hydrochloride trihydrate, 99%, Thermo Scientific™

Product Code	Brand	Quantity
15424769	Thermo Scientific Alfa Aesar J62370.MC	100mg
15434769	Thermo Scientific Alfa Aesar J62370.MD	250mg

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Chemical Identifiers

• CAS: 136572-09-3
• Molecular Weight (g/mol): 623.15
• InChI Key: GURKHSYORGJETM-WAQYZQTGSA-N
• PubChem CID: 74990
• IUPAC Name: hydrogen (19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl [1,4'-bipiperidine]-1'-carboxylate chloride

• Molecular Formula: C33H39ClN4O6
• MDL Number: MFCD01862255
• Synonym: irinotecan hydrochloride, irinotecan hcl, topotecin, campto, cpt-11, cpt 11, camptothecin 11 hydrochloride, camptothecin 11, unii-06x131e4oe
• ChEBI: CHEBI:5971
• SMILES: [H+].[Cl-].CCC1=C2C=C(OC(=O)N3CCC(CC3)N3CCCCC3)C=CC2=NC2=C1CN1C2=CC2=C(COC(=O)[C@]2(O)CC)C1=O

Specifications

• CAS: 136572-09-3
• MDL Number: MFCD01862255
• Synonym: irinotecan hydrochloride, irinotecan hcl, topotecin, campto, cpt-11, cpt 11, camptothecin 11 hydrochloride, camptothecin 11, unii-06x131e4oe
• InChI Key: GURKHSYORGJETM-WAQYZQTGSA-N
• IUPAC Name: hydrogen (19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0²,¹¹.0⁴,⁹.0¹⁵,²⁰]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl [1,4'-bipiperidine]-1'-carboxylate chloride
• PubChem CID: 74990
• Formula Weight: 677.19 (623.15 Anhydrous)
• Chemical Name or Material: Irinotecan hydrochloride trihydrate

• Molecular Formula: C33H39ClN4O6
• Merck Index: 14,5091
• Solubility Information: Soluble in DMSO at 100mg/ml; Soluble in water at 25mg/ml with warming
• SMILES: [H+].[Cl-].CCC1=C2C=C(OC(=O)N3CCC(CC3)N3CCCCC3)C=CC2=NC2=C1CN1C2=CC2=C(COC(=O)[C@]2(O)CC)C1=O
• Molecular Weight (g/mol): 623.15
• ChEBI: CHEBI:5971
• Percent Purity: 99%

Safety and Handling

GHS H Statement
H302
Harmful if swallowed.

P264b-P270-P301+P312-P330-P501c

H302

missing translation for 'rtecsNumber' : DW1060750

missing translation for 'tsca' : No

Recommended Storage : Keep cold

Product Identifier

• Irinotecan hydrochloride trihydrate

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 4
• Specific target organ toxicity Category 1

Hazard Statement

• H302-Harmful if swallowed.
• H372-Causes damage to organs.

Precautionary Statement

• P260-Do not breathe dust/fume/gas/mist/vapours/spray.
• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
• P312-Call a POISON CENTER/doctor/if you feel unwell.

Supplemental information

• MIXTURE LIST-Contains : Irinotecan hydrochloride trihydrate

RUO – Research Use Only