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  6. Invitrogen™ IRF8 Recombinant Rabbit Monoclonal Antibody (K01_1T06)

Invitrogen™ IRF8 Recombinant Rabbit Monoclonal Antibody (K01_1T06)

Product Code. 30826382
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Quantity:
50 μL
100 μL
Unit Size:
50µL
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30826382 100 μL -
30825808 50 μL 50µL
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Product Code. 30826382 Supplier Invitrogen™ Supplier No. MA563860

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Description

Rabbit Recombinant Monoclonal Antibody

IRF8 Recombinant Monoclonal Antibody for Western Blot

IRF8 (interferon regulatory factor 8) is a transcriptional activator or repressor. It specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes. IRF8 plays a negative regulatory role in cells of the immune system. It is involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells. This leads to recognition of AICE sequence, an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of the genes. Mutations in the gene can result in immunodeficiencey 32A and 32B.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRF8
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_1T06
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 150mM NaCl, 0.05% BSA, 40% glycerol and 0.01% sodium azide; pH 7.4
Gene Irf8
Gene Accession No. Q02556
Gene Alias AI893568; H-ICSBP; Icsbp; Icsbp1; IMD32A; IMD32B; interferon consensus sequence binding protein 1; Interferon consensus sequence-binding protein; Interferon regulatory factor 8; Irf8; IRF-8; Myls; transcription factor ICSBP
Gene Symbols Irf8
Host Species Rabbit
Immunogen Recombinant protein of human IRF8.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3394
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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