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Invitrogen™ IRF7 Polyclonal Antibody

Product Code. 12818422
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12818422 100 μg 100µg
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Product Code. 12818422 Supplier Invitrogen™ Supplier No. PA520281

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Description

Rabbit Polyclonal Antibody

A suggested positive control is 293 cell lysate. PA5-20281 can be used with blocking peptide PEP-0415.

Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRF7
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene IRF7
Gene Accession No. P70434, Q92985
Gene Alias IMD39; Interferon regulatory factor 7; interferon regulatory factor-7H; Irf7; IRF-7; IRF7A; IRF7B; IRF7C; IRF7H; IRF-7H
Gene Symbols IRF7
Host Species Rabbit
Immunogen A peptide corresponding to 14 amino acids near the center of human IRF7.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3665, 54123
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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