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IRAK4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen 365500
Code : 50
Additional Details : Weight : 0.50000kg
Description
IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways. Overexpression of IRAK-4 activates NF-kappa-B and MAPK pathways. IRAK-4 interacts with and phosphorylates IRAK-1. IRAK-4-deficient animals are completely resistant to the challenge with LPS. Animals and humans lacking IRAK-4 are impaired in their responses to viral and bacterial challenges. Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses and in innate immunity.Specifications
IRAK4 | |
Polyclonal | |
Unconjugated | |
IRAK4 | |
8430405M07Rik; 9330209D03Rik; interleukin 1 receptor associated kinase 4; interleukin-1; interleukin-1 receptor-associated kinase 4; IPD1; Irak4; IRAK-4; NY-REN-64; REN64; renal carcinoma antigen NY-REN-64 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
266632, 51135 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
0.25 mg/mL | |
PBS with 0.1% sodium azide; pH 7.4 | |
Q8R4K2, Q9NWZ3 | |
IRAK4 | |
Synthetic peptide derived from the N-terminal region of the human IRAK4 (IL-1 receptor associated kinase 4) protein. | |
100 μg | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |